Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation

PURPOSE: Isocitrate dehydrogenase 1 (IDH1) mutations are associated with improved survival in gliomas. Depending on the IDH1 status, TERT promoter mutations affect prognosis. IDH1 mutations are associated with alpha-thalassemia/mental retardation syndrome X-linked (ATRX) mutations and alternative le...

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Publicat a:J Neurooncol
Autors principals: Ferreira, Monica Sofia Ventura, Sørensen, Mia Dahl, Pusch, Stefan, Beier, Dagmar, Bouillon, Anne-Sophie, Kristensen, Bjarne Winther, Brümmendorf, Tim Henrik, Beier, Christoph Patrick, Beier, Fabian
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
Matèries:
Laboratory Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076064/
https://ncbi.nlm.nih.gov/pubmed/31960234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-020-03394-y
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