Therapeutic Targets for the Treatment of Cardiac Fibrosis and Cancer: Focusing on TGF-β Signaling

Transforming growth factor-β (TGF-β) is a common mediator of cancer progression and fibrosis. Fibrosis can be a significant pathology in multiple organs, including the heart. In this review, we explain how inhibitors of TGF-β signaling can work as antifibrotic therapy. After cardiac injury, profibro...

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Bibliographic Details
Published in:Front Cardiovasc Med
Main Authors: Parichatikanond, Warisara, Luangmonkong, Theerut, Mangmool, Supachoke, Kurose, Hitoshi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cardiovascular Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075814/
https://ncbi.nlm.nih.gov/pubmed/32211422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.00034
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