Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury

Infection with avian influenza A H5N1 virus results in acute lung injury (ALI) and has a high mortality rate (52.79%) because there are limited therapies available for treatment. Drug repositioning is an economical approach to drug discovery. We developed a method for drug repositioning based on hig...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Huang, Fengming, Zhang, Cong, Liu, Qiang, Zhao, Yan, Zhang, Yuqing, Qin, Yuhao, Li, Xiao, Li, Chang, Zhou, Congzhao, Jin, Ningyi, Jiang, Chengyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075543/
https://ncbi.nlm.nih.gov/pubmed/32176725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008341
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