Predicting HLA class II antigen presentation through integrated deep learning

Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II molecules would be valuable for vaccine development and cancer immunotherapies. Current computational methods trained on in vitro binding data are limited by insufficient training data and algorithmic constraints....

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Bibliografske podrobnosti
izdano v:Nat Biotechnol
Main Authors: Chen, Binbin, Khodadoust, Michael S., Olsson, Niclas, Wagar, Lisa E., Fast, Ethan, Liu, Chih Long, Muftuoglu, Yagmur, Sworder, Brian J., Diehn, Maximilian, Levy, Ronald, Davis, Mark M., Elias, Joshua E., Altman, Russ B., Alizadeh, Ash A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075463/
https://ncbi.nlm.nih.gov/pubmed/31611695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0280-2
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