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Direct Vicinal Difunctionalization of Thiophenes Enabled by the Palladium/Norbornene Cooperative Catalysis

Herein we report a direct vicinal difunctionalization of thiophenes via the palladium/norbornene (Pd/NBE) cooperative catalysis. A series of mono- and disubstituted thiophenes can be difunctionalized site-selectively and regioselectively at the C4 and C5 positions in good yields, enabled by an arsin...

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Pubblicato in:J Am Chem Soc
Autori principali: Li, Renhe, Zhou, Yun, Xu, Xiaolong, Dong, Guangbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075341/
https://ncbi.nlm.nih.gov/pubmed/31744291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10857
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