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Ppp1r1b-lncRNA inhibits PRC2 at myogenic regulatory genes to promote cardiac and skeletal muscle development in mouse and human

Long noncoding RNAs (lncRNAs) have emerged as critical epigenetic regulators and play important roles in cardiac development and congenital heart disease. In a previous study, we identified a novel lncRNA, Ppp1r1b, with expression highly correlated with myogenesis. However, the molecular mechanism t...

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Detalles Bibliográficos
Publicado en:RNA
Main Authors: Kang, Xuedong, Zhao, Yan, Van Arsdell, Glen, Nelson, Stanley F., Touma, Marlin
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075267/
https://ncbi.nlm.nih.gov/pubmed/31953255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073692.119
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