Functions of Enyolreductase (ER) Domains of PKS Cluster in Lipid Synthesis and Enhancement of PUFAs Accumulation in Schizochytrium limacinum SR21 Using Triclosan as a Regulator of ER

The polyketide synthase (PKS) cluster genes are supposed to synthesize polyunsaturated fatty acids (PUFAs) in S. limacinum. In this study, two enyolreductase (ER) genes located on PKS cluster were knocked out through homologous recombination to explore their functions. The knock-out of OrfB-ER (loca...

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Ling, Xueping, Zhou, Hao, Yang, Qinghua, Yu, Shengyang, Li, Jun, Li, Zhipeng, He, Ning, Chen, Cuixue, Lu, Yinghua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074904/
https://ncbi.nlm.nih.gov/pubmed/32098234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms8020300
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