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The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions

Inflammasomes are intracellular multiprotein complexes in the cytoplasm that regulate inflammation activation in the innate immune system in response to pathogens and to host self-derived molecules. Recent advances greatly improved our understanding of the activation of nucleotide-binding oligomeriz...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Pirzada, Rameez Hassan, Javaid, Nasir, Choi, Sangdun
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074480/
https://ncbi.nlm.nih.gov/pubmed/32012695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020131
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