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Molecular Bases of Neurodegeneration and Cognitive Decline, the Major Burden of Sanfilippo Disease

The mucopolysaccharidoses (MPS) are a group of diseases caused by the lysosomal accumulation of glycosaminoglycans, due to genetic deficiencies of enzymes involved in their degradation. MPS III or Sanfilippo disease, in particular, is characterized by early-onset severe, progressive neurodegeneratio...

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Podrobná bibliografie
Vydáno v:J Clin Med
Hlavní autoři: Heon-Roberts, Rachel, Nguyen, Annie L. A., Pshezhetsky, Alexey V.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074161/
https://ncbi.nlm.nih.gov/pubmed/32012694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9020344
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