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Photoprotective Activity of Topsentin, A Bis(Indole) Alkaloid from the Marine Sponge Spongosorites genitrix, by Regulation of COX-2 and Mir-4485 Expression in UVB-Irradiated Human Keratinocyte Cells

Skin is an important barrier to protect the body from environmental stress. However, exposure to ultraviolet radiation (UV) and various environmental oxidative stresses can cause skin inflammation. Cyclooxygenase-2 (COX-2) is an inducible enzyme that mediates the formation of prostaglandin E(2) (PGE...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Hwang, Jiyoung, Kim, Donghwa, Park, Jae Sung, Park, Hyen Joo, Shin, Jongheon, Lee, Sang Kook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073676/
https://ncbi.nlm.nih.gov/pubmed/32013063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18020087
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