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Heteroplasmy and Copy Number in the Common m.3243A>G Mutation—A Post-Mortem Genotype–Phenotype Analysis

Different mitochondrial DNA (mtDNA) mutations have been identified to cause mitochondrial encephalopathy, lactate acidosis and stroke-like episodes (MELAS). The underlying genetic cause leading to an enormous clinical heterogeneity associated with m.3243A>G-related mitochondrial diseases is still...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Motlagh Scholle, Leila, Zierz, Stephan, Mawrin, Christian, Wickenhauser, Claudia, Lehmann Urban, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073558/
https://ncbi.nlm.nih.gov/pubmed/32085658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11020212
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