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Combination of Decitabine and Entinostat Synergistically Inhibits Urothelial Bladder Cancer Cells via Activation of FoxO1

Occurrence of cisplatin-resistance in bladder cancer is frequent and results in disease progression. Thus, novel therapeutic approaches are a high medical need for patients suffering from chemotherapy failure. The purpose of this study was to test the combination of the DNA methyltransferase inhibit...

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Publicat a:Cancers (Basel)
Autors principals: Wang, Chenyin, Hamacher, Alexandra, Petzsch, Patrick, Köhrer, Karl, Niegisch, Günter, Hoffmann, Michèle J., Schulz, Wolfgang A., Kassack, Matthias U.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073167/
https://ncbi.nlm.nih.gov/pubmed/32028599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020337
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