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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD

In inflammatory bowel disease (IBD), the intestinal epithelium is characterized by increased permeability both in active disease and remission states. The genetic underpinnings of this increased intestinal permeability are largely unstudied, in part due to a lack of appropriate modelling systems. Ou...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Gleeson, John P., Estrada, Hannah Q., Yamashita, Michifumi, Svendsen, Clive N., Targan, Stephan R., Barrett, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073090/
https://ncbi.nlm.nih.gov/pubmed/32093254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041438
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