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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD

In inflammatory bowel disease (IBD), the intestinal epithelium is characterized by increased permeability both in active disease and remission states. The genetic underpinnings of this increased intestinal permeability are largely unstudied, in part due to a lack of appropriate modelling systems. Ou...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Gleeson, John P., Estrada, Hannah Q., Yamashita, Michifumi, Svendsen, Clive N., Targan, Stephan R., Barrett, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073090/
https://ncbi.nlm.nih.gov/pubmed/32093254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041438
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