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Hypoxia-Dependent Expression of TG2 Isoforms in Neuroblastoma Cells as Consequence of Different MYCN Amplification Status

Transglutaminase 2 (TG2) is a multifunctional enzyme and two isoforms, TG2-L and TG2-S, exerting opposite effects in the regulation of cell death and survival, have been revealed in cancer tissues. Notably, in cancer cells a hypoxic environment may stimulate tumor growth, invasion and metastasis. He...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Currò, Monica, Ferlazzo, Nadia, Giunta, Maria Laura, Montalto, Angela Simona, Russo, Tiziana, Arena, Salvatore, Impellizzeri, Pietro, Caccamo, Daniela, Romeo, Carmelo, Ientile, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072980/
https://ncbi.nlm.nih.gov/pubmed/32085516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041364
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