Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin

The efficacy of cisplatin-based chemotherapy in ovarian cancer is often limited by the development of drug resistance. In most ovarian cancer cells, cisplatin activates extracellular signal-regulated kinase1/2 (ERK1/2) signalling. Phosphoprotein enriched in astrocytes (PEA-15) is a ubiquitously expr...

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Pubblicato in:Cells
Autori principali: Dilruba, Shahana, Grondana, Alessia, Schiedel, Anke C., Ueno, Naoto T., Bartholomeusz, Chandra, Cinatl Jr, Jindrich, McLaughlin, Katie-May, Wass, Mark N., Michaelis, Martin, Kalayda, Ganna V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072772/
https://ncbi.nlm.nih.gov/pubmed/32102425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020515
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