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Is Desmin Propensity to Aggregate Part of its Protective Function?

Desmin is the major protein component of the intermediate filaments (IFs) cytoskeleton in muscle cells, including cardiac. The accumulation of cleaved and misfolded desmin is a cellular hallmark of heart failure (HF). These desmin alterations are reversed by therapy, suggesting a causal role for the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cells
मुख्य लेखकों: Singh, Sonia R., Kadioglu, Hikmet, Patel, Krishna, Carrier, Lucie, Agnetti, Giulio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072738/
https://ncbi.nlm.nih.gov/pubmed/32093415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020491
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