The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets

The cell cycle is controlled by microtubule-associated serine/threonine kinase-like (MASTL), which phosphorylates the cAMP-regulated phosphoproteins 19 (ARPP19) at S62 and 19e/α-endosulfine (ENSA) at S67and converts them into protein phosphatase 2A (PP2A) inhibitors. Based on initial proteomic data,...

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Vydáno v:Cells
Hlavní autoři: Kumm, Elena J., Pagel, Oliver, Gambaryan, Stepan, Walter, Ulrich, Zahedi, René P., Smolenski, Albert, Jurk, Kerstin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072724/
https://ncbi.nlm.nih.gov/pubmed/32085646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020472
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