Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Prognostic and Targetable Biomarkers, Changing the Vision from a Localized Tumor to a Systemic Pathology

Circulating platelets (PLTs) are able to affect glioblastoma (GBM) microenvironment by supplying oncopromoter and pro-angiogenic factors. Among these mediators, sphingosine-1-phophate (S1P) has emerged as a potent bioactive lipid enhancing cell proliferation and survival. Here, we investigated the e...

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Bibliographic Details
Published in:Cells
Main Authors: Campanella, Rolando, Guarnaccia, Laura, Cordiglieri, Chiara, Trombetta, Elena, Caroli, Manuela, Carrabba, Giorgio, La Verde, Nicla, Rampini, Paolo, Gaudino, Chiara, Costa, Antonella, Luzzi, Sabino, Mantovani, Giovanna, Locatelli, Marco, Riboni, Laura, Navone, Stefania Elena, Marfia, Giovanni
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072723/
https://ncbi.nlm.nih.gov/pubmed/31991805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020294
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