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Nicotine Induces IL-8 Secretion from Pancreatic Cancer Stroma and Worsens Cancer-Induced Cachexia

Smoking is highly associated with pancreatic cancer. Nicotine, the addictive component of tobacco, is involved in pancreatic cancer tumorigenesis, metastasis, and chemoresistance. This work aimed to describe the role of nicotine within the pancreatic cancer tumor microenvironment. Nicotine treatment...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Underwood, Patrick W., Zhang, Dong Yu, Cameron, Miles E., Gerber, Michael H., Delitto, Daniel, Maduka, Michael U., Cooper, Kyle J., Han, Song, Hughes, Steven J., Judge, Sarah M., Judge, Andrew R., Trevino, Jose G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072641/
https://ncbi.nlm.nih.gov/pubmed/32024069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020329
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