Nicotine Induces IL-8 Secretion from Pancreatic Cancer Stroma and Worsens Cancer-Induced Cachexia

Smoking is highly associated with pancreatic cancer. Nicotine, the addictive component of tobacco, is involved in pancreatic cancer tumorigenesis, metastasis, and chemoresistance. This work aimed to describe the role of nicotine within the pancreatic cancer tumor microenvironment. Nicotine treatment...

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Pubblicato in:Cancers (Basel)
Autori principali: Underwood, Patrick W., Zhang, Dong Yu, Cameron, Miles E., Gerber, Michael H., Delitto, Daniel, Maduka, Michael U., Cooper, Kyle J., Han, Song, Hughes, Steven J., Judge, Sarah M., Judge, Andrew R., Trevino, Jose G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072641/
https://ncbi.nlm.nih.gov/pubmed/32024069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020329
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