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CD22 Expression in B-Cell Acute Lymphoblastic Leukemia: Biological Significance and Implications for Inotuzumab Therapy in Adults

CD22 is a surface molecule expressed early during the ontogeny of B cells in the bone marrow and spleen, and can be found on B cells isolated from the different lymphoid compartments in humans. CD22 is expressed by most blasts from the majority (60–90%) of B-cell acute lymphoblastic leukemia (B-ALL)...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lanza, Francesco, Maffini, Enrico, Rondoni, Michela, Massari, Evita, Faini, Angelo Corso, Malavasi, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072635/
https://ncbi.nlm.nih.gov/pubmed/32012891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020303
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