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Interleukin-6 Derived from the Central Nervous System May Influence the Pathogenesis of Experimental Autoimmune Encephalomyelitis in a Cell-Dependent Manner

Background: Interleukin-6 (IL-6) is a pleiotropic and multifunctional cytokine that plays a critical role in induction of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Although EAE has always been considered a peripherally elicited disease, Il6 expression...

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Publicado en:Cells
Autores principales: Sanchis, Paula, Fernández-Gayol, Olaya, Comes, Gemma, Escrig, Anna, Giralt, Mercedes, Palmiter, Richard D., Hidalgo, Juan
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072597/
https://ncbi.nlm.nih.gov/pubmed/32023844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020330
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