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Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients

The efficiency of chemotherapy drugs can be affected by ATP-binding cassette (ABC) transporter expression or by their mutation status. Multidrug resistance is linked with ABC transporter overexpression. In the present study, we performed rare mutation analyses for 12 ABC transporters related to drug...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Kadioglu, Onat, Saeed, Mohamed, Munder, Markus, Spuller, Andreas, Greten, Henry Johannes, Efferth, Thomas
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072590/
https://ncbi.nlm.nih.gov/pubmed/31991926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020299
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