Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids

Radiation-induced normal tissue toxicity often limits the curative treatment of cancer. Moreover, normal tissue relative biological effectiveness data for high-linear energy transfer particles are urgently needed. We propose a strategy based on transcriptome analysis of patient-derived human intesti...

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Publicat a:Cancers (Basel)
Autors principals: Nowrouzi, Ali, Sertorio, Mathieu G., Akbarpour, Mahdi, Knoll, Maximillian, Krunic, Damir, Kuhar, Matthew, Schwager, Christian, Brons, Stephan, Debus, Jürgen, Wells, Susanne I., Wells, James M., Abdollahi, Amir
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072449/
https://ncbi.nlm.nih.gov/pubmed/32085439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020469
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