Metabolism of Estrogens: Turnover Differs between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells

High-grade serous ovarian cancer (HGSOC) is currently treated with cytoreductive surgery and platinum-based chemotherapy. The majority of patients show a primary response; however, many rapidly develop drug resistance. Antiestrogens have been studied as low toxic treatment options for HGSOC, with hi...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Poschner, Stefan, Wackerlig, Judith, Castillo-Tong, Dan Cacsire, Wolf, Andrea, von der Decken, Isabel, Rižner, Tea Lanišnik, Pavlič, Renata, Meshcheryakova, Anastasia, Mechtcheriakova, Diana, Fritzer-Szekeres, Monika, Thalhammer, Theresia, Jäger, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072378/
https://ncbi.nlm.nih.gov/pubmed/31979221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020279
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