Increased Expression of Micro-RNA-23a Mediates Chemoresistance to Cytarabine in Acute Myeloid Leukemia

Resistance to chemotherapy is one of the primary obstacles in acute myeloid leukemia (AML) therapy. Micro-RNA-23a (miR-23a) is frequently deregulated in AML and has been linked to chemoresistance in solid cancers. We, therefore, studied its role in chemoresistance to cytarabine (AraC), which forms t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Hatzl, Stefan, Perfler, Bianca, Wurm, Sonja, Uhl, Barbara, Quehenberger, Franz, Ebner, Susanne, Troppmair, Jakob, Reinisch, Andreas, Wölfler, Albert, Sill, Heinz, Zebisch, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072365/
https://ncbi.nlm.nih.gov/pubmed/32093419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020496
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