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Obesity Promotes Cooperation of Cancer Stem-Like Cells and Macrophages to Enhance Mammary Tumor Angiogenesis

Obesity is correlated with worsened prognosis and treatment resistance in breast cancer. Macrophage-targeted therapies are currently in clinical trials, however, little is known about how obesity may impact treatment efficacy. Within breast adipose tissue, obesity leads to chronic, macrophage-driven...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Hillers-Ziemer, Lauren E., McMahon, Rachel Q., Hietpas, Margaret, Paderta, Gretchen, LeBeau, Jennelle, McCready, Jessica, Arendt, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072330/
https://ncbi.nlm.nih.gov/pubmed/32098183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020502
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