Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma

Background: Inevitable recurrence after radiochemotherapy is the major problem in the treatment of glioblastoma, the most prevalent type of adult brain malignancy. Glioblastomas are notorious for a high degree of intratumor heterogeneity manifest through a diversity of cell types and molecular patte...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kim, Ella L., Sorokin, Maxim, Kantelhardt, Sven Rainer, Kalasauskas, Darius, Sprang, Bettina, Fauss, Julian, Ringel, Florian, Garazha, Andrew, Albert, Eugene, Gaifullin, Nurshat, Hartmann, Christian, Naumann, Nicole, Bikar, Sven-Ernö, Giese, Alf, Buzdin, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072286/
https://ncbi.nlm.nih.gov/pubmed/32102350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020520
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