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Mesothelial-to-Mesenchymal Transition Contributes to the Generation of Carcinoma-Associated Fibroblasts in Locally Advanced Primary Colorectal Carcinomas

During peritoneal metastasis, cancer cells spread from abdominal solid tumors, disseminate through the peritoneal fluid and attach to and invade through mesothelial cells (MCs) that line the peritoneum. Intestinal adenocarcinomas originating in the mucosa infiltrate the submucosa, muscle layer, and...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Gordillo, Carlos H., Sandoval, Pilar, Muñoz-Hernández, Patricia, Pascual-Antón, Lucía, López-Cabrera, Manuel, Jiménez-Heffernan, José A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072259/
https://ncbi.nlm.nih.gov/pubmed/32098058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020499
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