Long noncoding RNA lncARSR promotes nonalcoholic fatty liver disease and hepatocellular carcinoma by promoting YAP1 and activating the IRS2/AKT pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is the main cause for hepatocellular carcinoma (HCC). This study was intended to identify the function of long non-coding RNA (lncRNA) lncARSR in NAFLD and its role in human HCC cells (HepG2) proliferation and invasion. METHODS: LncARSR expression...

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Vydáno v:J Transl Med
Hlavní autoři: Chi, Yuan, Gong, Zheng, Xin, He, Wang, Ziwen, Liu, Zhaoyu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071718/
https://ncbi.nlm.nih.gov/pubmed/32169080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02225-y
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