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Amyloidogenic Peptides in Human Neuro-Degenerative Diseases and in Microorganisms: A Sorrow Shared Is a Sorrow Halved?

The term “amyloid” refers to proteinaceous deposits of peptides that might be generated from larger precursor proteins e.g., by proteolysis. Common to these peptides is a stable cross-β dominated secondary structure which allows self-assembly, leading to insoluble oligomers and lastly to fibrils. Th...

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Bibliographic Details
Published in:Molecules
Main Author: Endres, Kristina
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070710/
https://ncbi.nlm.nih.gov/pubmed/32093040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040925
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