Betulinic Acid-Nitrogen Heterocyclic Derivatives: Design, Synthesis, and Antitumor Evaluation in Vitro

Betulinic acid (BA) is a star member of the pentacyclic triterpenoid family, which exhibits great prospects for antitumor drug development. In an attempt to develop novel antitumor candidates, 21 BA-nitrogen heterocyclic derivatives were synthetized, in addition to four intermediates, 23 of which we...

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Publicado no:Molecules
Main Authors: Yang, Yuqin, Xie, Tianxin, Tian, Xuehao, Han, Nana, Liu, Xiaojing, Chen, Hongshan, Qi, Jinchai, Gao, Feng, Li, Wen, Wu, Qianwen, Huo, Su, Gu, Yuhao, Dai, Ziqi, Wang, Penglong, Lei, Haimin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070564/
https://ncbi.nlm.nih.gov/pubmed/32093264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040948
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