Reconstitution of TCA cycle involving l-isoleucine dioxygenase for hydroxylation of l-isoleucine in Escherichia coli using CRISPR-Cas9

l-isoleucine dioxygenase (IDO) is an Fe (II)/α-ketoglutarate (α-KG)-dependent dioxygenase that specifically converts l-isoleucine (l-Ile) to (2S, 3R, 4S)-4-hydroxyisoleucine (4-HIL). 4-HIL is an important drug for the treatment and prevention of type 1 and type 2 diabetes but the yields using curren...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:3 Biotech
Asıl Yazarlar: An, Jianhong, Zhang, Wenli, Jing, Xiaoran, Nie, Yao, Xu, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2020
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070131/
https://ncbi.nlm.nih.gov/pubmed/32206501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-020-2160-3
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller