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The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation

Deleted in azoospermia-like (DAZL) is an RNA-binding protein critical for gamete development. In full-grown oocytes, the DAZL protein increases 4-fold during reentry into the meiotic cell cycle. Here, we have investigated the functional significance of this accumulation at a genome-wide level. Deple...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yang, Cai-Rong, Rajkovic, Gabriel, Daldello, Enrico Maria, Luong, Xuan G., Chen, Jing, Conti, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070028/
https://ncbi.nlm.nih.gov/pubmed/32170089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15209-9
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