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Quantification of the overall contribution of gene-environment interaction for obesity-related traits

The growing sample size of genome-wide association studies has facilitated the discovery of gene-environment interactions (GxE). Here we propose a maximum likelihood method to estimate the contribution of GxE to continuous traits taking into account all interacting environmental variables, without t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sulc, Jonathan, Mounier, Ninon, Günther, Felix, Winkler, Thomas, Wood, Andrew R., Frayling, Timothy M., Heid, Iris M., Robinson, Matthew R., Kutalik, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070002/
https://ncbi.nlm.nih.gov/pubmed/32170055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15107-0
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