IL6-receptor antibody tocilizumab as salvage therapy in severe chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: a retrospective analysis

Chronic graft-versus-host disease (cGvHD) remains the most relevant factor affecting survival after allogeneic hematopoietic stem cell transplantation (alloHSCT). Besides corticosteroids (and ibrutinib in the USA), there is no established therapy for cGvHD. Tocilizumab, a humanized IgG1 IL6-receptor...

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Detalhes bibliográficos
Publicado no:Ann Hematol
Main Authors: Kattner, Anna-Sophia, Holler, Ernst, Holler, Barbara, Klobuch, Sebastian, Weber, Daniela, Martinovic, Danilo, Edinger, Matthias, Herr, Wolfgang, Wolff, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069928/
https://ncbi.nlm.nih.gov/pubmed/32086584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-020-03968-w
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