Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801

The biosynthesis of the essential metabolic cofactor coenzyme A (CoA) has been receiving increasing attention as a new target that shows potential to counter the rising resistance to established antimicrobials. In particular, phosphopantothenoylcysteine synthetase (PPCS)—the second CoA biosynthesis...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Medchemcomm
Huvudupphovsmän: Domingo, Riyad, van der Westhuyzen, Renier, Hamann, Anton R., Mostert, Konrad J., Barnard, Leanne, Paquet, Tanya, Tjhin, Erick T., Saliba, Kevin J., van Otterlo, Willem A. L., Strauss, Erick
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2019
Ämnen:
Chemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069524/
https://ncbi.nlm.nih.gov/pubmed/32206243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00312f
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk