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Readily accessible sp(3)-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality
Increased molecular complexity correlates with improved chances of success in the drug development process. Here, a strategy for the creation of sp(3)-rich, non-planar heterocyclic scaffolds suitable for drug discovery is described that obviates the need to generate multiple stereogenic centers with...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069508/ https://ncbi.nlm.nih.gov/pubmed/32206282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04849a |
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