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Construction of a self-directed replication system for label-free and real-time sensing of repair glycosylases with zero background

Genomic DNA damage and repair are involved in multiple fundamental biological processes, including metabolism, disease, and aging. Inspired by the natural repair mechanism in vivo, we demonstrate for the first time the construction of a self-directed replication system for label-free and real-time s...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wang, Li-juan, Lu, Ying-ying, Zhang, Chun-yang
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069502/
https://ncbi.nlm.nih.gov/pubmed/32206275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04738g
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