Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim

OBJECTIVES: Eumycetoma is currently treated with a combination of itraconazole therapy and surgery, with limited success. Recently, olorofim, the lead candidate of the orotomides, a novel class of antifungal agents, entered a Phase II trial for the treatment of invasive fungal infections. Here we de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Antimicrob Chemother
Prif Awduron: Lim, Wilson, Eadie, Kimberly, Konings, Mickey, Rijnders, Bart, Fahal, Ahmed H, Oliver, Jason D, Birch, Mike, Verbon, Annelies, van de Sande, Wendy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069493/
https://ncbi.nlm.nih.gov/pubmed/31904836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz529
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