Accurately estimating the length distributions of genomic micro-satellites by tumor purity deconvolution

BACKGROUND: Genomic micro-satellites are the genomic regions that consist of short and repetitive DNA motifs. Estimating the length distribution and state of a micro-satellite region is an important computational step in cancer sequencing data pipelines, which is suggested to facilitate the downstre...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Wang, Yixuan, Zhang, Xuanping, Xiao, Xiao, Zhang, Fei-Ran, Yan, Xinxing, Feng, Xuan, Zhao, Zhongmeng, Guan, Yanfang, Wang, Jiayin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069170/
https://ncbi.nlm.nih.gov/pubmed/32164528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3349-5
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