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Network hub-node prioritization of gene regulation with intra-network association

BACKGROUND: To identify and prioritize the influential hub genes in a gene-set or biological pathway, most analyses rely on calculation of marginal effects or tests of statistical significance. These procedures may be inappropriate since hub nodes are common connection points and therefore may inter...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Chang, Hung-Ching, Chu, Chiao-Pei, Lin, Shu-Ju, Hsiao, Chuhsing Kate
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069025/
https://ncbi.nlm.nih.gov/pubmed/32164570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3444-7
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