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Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy

BACKGROUND: Rapamycin is known to be effective in suppressing senescence and the senescence-associated secretory phenotype (SASP). Therefore, it is highly expected to represent an anti-aging drug. Its anti-aging effect has been demonstrated at the mouse individual level. However, there are not many...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Sasaki, Norihiko, Itakura, Yoko, Toyoda, Masashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069020/
https://ncbi.nlm.nih.gov/pubmed/32164764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00533-w
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