Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy – the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial

ABSTRACT: Compelling data have linked disease progression in patients with idiopathic pulmonary fibrosis (IPF) with lung dysbiosis and the resulting dysregulated local and systemic immune response. Moreover, prior therapeutic trials have suggested improved outcomes in these patients treated with eit...

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Detalhes bibliográficos
Publicado no:Respir Res
Principais autores: Anstrom, Kevin J., Noth, Imre, Flaherty, Kevin R., Edwards, Rex H., Albright, Joan, Baucom, Amanda, Brooks, Maria, Clark, Allan B., Clausen, Emily S., Durheim, Michael T., Kim, Dong-Yun, Kirchner, Jerry, Oldham, Justin M., Snyder, Laurie D., Wilson, Andrew M., Wisniewski, Stephen R., Yow, Eric, Martinez, Fernando J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069004/
https://ncbi.nlm.nih.gov/pubmed/32164673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-1326-1
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