Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing

BACKGROUND: Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by recurring structural chromosomal alterations and genetic alterations, whose detection is critical in diagnosis, risk stratification and prognostication. However, the genetic mechanisms that give...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Zhang, Honghong, Wang, Hongsheng, Qian, Xiaowen, Gao, Shuai, Xia, Jieqi, Liu, Junwen, Cheng, Yanqin, Man, Jie, Zhai, Xiaowen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068927/
https://ncbi.nlm.nih.gov/pubmed/32164600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6709-7
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