Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing

BACKGROUND: Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by recurring structural chromosomal alterations and genetic alterations, whose detection is critical in diagnosis, risk stratification and prognostication. However, the genetic mechanisms that give...

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Vydáno v:BMC Cancer
Hlavní autoři: Zhang, Honghong, Wang, Hongsheng, Qian, Xiaowen, Gao, Shuai, Xia, Jieqi, Liu, Junwen, Cheng, Yanqin, Man, Jie, Zhai, Xiaowen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068927/
https://ncbi.nlm.nih.gov/pubmed/32164600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6709-7
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