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Allergen and Ozone Exacerbate Serotonin-Induced Increases in Airway Smooth Muscle Contraction in a Model of Childhood Asthma

BACKGROUND: Serotonin (5-HT) modulates cholinergic neurotransmission and exacerbates airway smooth muscle (ASM) contraction in normal animal and nonasthmatic human tissue. Exposure to house dust mite allergen (HDMA) and ozone (O<sub>3</sub>) leads to airway hyperreactivity and 5-HT-posit...

詳細記述

保存先:
書誌詳細
出版年:Respiration
主要な著者: Moore, Brian D., Hyde, Dallas, Miller, Lisa, Wong, Emily, Frelinger, Jessica, Schelegle, Edward S.
フォーマット: Artigo
言語:Inglês
出版事項: S. Karger AG 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068792/
https://ncbi.nlm.nih.gov/pubmed/22507883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336835
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