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Allergen and Ozone Exacerbate Serotonin-Induced Increases in Airway Smooth Muscle Contraction in a Model of Childhood Asthma
BACKGROUND: Serotonin (5-HT) modulates cholinergic neurotransmission and exacerbates airway smooth muscle (ASM) contraction in normal animal and nonasthmatic human tissue. Exposure to house dust mite allergen (HDMA) and ozone (O<sub>3</sub>) leads to airway hyperreactivity and 5-HT-posit...
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| 出版年: | Respiration |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
S. Karger AG
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7068792/ https://ncbi.nlm.nih.gov/pubmed/22507883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336835 |
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