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Allergen and Ozone Exacerbate Serotonin-Induced Increases in Airway Smooth Muscle Contraction in a Model of Childhood Asthma
BACKGROUND: Serotonin (5-HT) modulates cholinergic neurotransmission and exacerbates airway smooth muscle (ASM) contraction in normal animal and nonasthmatic human tissue. Exposure to house dust mite allergen (HDMA) and ozone (O<sub>3</sub>) leads to airway hyperreactivity and 5-HT-posit...
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| Publicado en: | Respiration |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
S. Karger AG
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7068792/ https://ncbi.nlm.nih.gov/pubmed/22507883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000336835 |
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