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Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms

Carteolol is a non-selective β-adrenoceptor antagonist used for the treatment of glaucoma, and its abuse might be cytotoxic to the cornea. However, its cytotoxicity and underlying mechanisms need to be elucidated. Herein, we used an in vivo model of feline corneas and an in vitro model of human corn...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Su, Wen, Zhao, Jun, Fan, Ting-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068677/
https://ncbi.nlm.nih.gov/pubmed/32210806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00202
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