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Double-Blind Placebo-Controlled Pilot Investigation of the Safety of a Single Dose of Rapid-Acting Intranasal Insulin in Down Syndrome

BACKGROUND: Individuals with Down syndrome are likely to develop clinical and neuropathological brain changes resembling Alzheimer’s disease dementia by the ages of 35–40 years. Intranasal insulin is a potential treatment for neurodegenerative disease that has been shown to reduce amyloid plaque bur...

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Bibliografiske detaljer
Udgivet i:Drugs R D
Main Authors: Rosenbloom, Michael, Barclay, Terry, Johnsen, Justin, Erickson, Lauren, Svitak, Aleta, Pyle, Maria, Frey, William, Hanson, Leah R.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067723/
https://ncbi.nlm.nih.gov/pubmed/32077057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-020-00296-2
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