Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study

STUDY QUESTION: Is the age of onset of pubertal markers related to subsequent changes in DNA methylation (DNAm)? SUMMARY ANSWER: We identified 273 cytosine-phosphate-guanine (CpG) dinucleotides in girls and 67 CpGs in boys that were related to puberty and that were replicable in two other investigat...

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Bibliographic Details
Published in:Hum Reprod Open
Main Authors: Chen, Su, Refaey, Hala, Mukherjee, Nandini, Solatikia, Farnaz, Jiang, Yu, Arshad, S Hasan, Ewart, Susan, Holloway, John W, Zhang, Hongmei, Karmaus, Wilfried
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067683/
https://ncbi.nlm.nih.gov/pubmed/32190749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hropen/hoaa006
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