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Identification of C10 nitrogen-containing aporphines with dopamine D(1) versus D(5) receptor selectivity
New aporphines containing C10 nitrogen substituents (viz. nitro, aniline or amide moieties), were synthesized and evaluated for affinity at human serotonin 5-HT(1A) and 5-HT(2A) receptors and at human dopamine D(1), D(2) and D(5) receptors. Two series of analogs were investigated: series A which con...
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| 出版年: | Bioorg Med Chem Lett |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7067653/ https://ncbi.nlm.nih.gov/pubmed/32107165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127053 |
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