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Prostaglandins and Other Lipid Mediators Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases

Cytochrome P450 (CYP) metabolism of arachidonic acid (ARA) produces epoxy fatty acids (EpFAs) such as epoxyeicosatrienoic acids (EETs) that are known to exert protective effects in inflammatory disorders. Endogenous EpFAs are further metabolized into corresponding diols by the soluble epoxide hydrol...

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Bibliografiske detaljer
Udgivet i:Prostaglandins Other Lipid Mediat
Main Authors: Atone, Jogen, Wagner, Karen, Hashimoto, Kenji, Hammock, Bruce D.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067627/
https://ncbi.nlm.nih.gov/pubmed/31698143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2019.106385
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